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Faculty Research Interests
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This page provides an alphabetical listing of biomedical graduate program faculty at Georgetown University Medical Center, along with a brief description of their research interests.

You can access further information about each faculty member by clicking on their name.

By using the Edit/Find function on your navigational toolbar, you can search for keywords of interest to you on this page (such as "apoptosis", "plasticity", or "metastasis", for example) to identify faculty conducting research that includes that word in the description of their research interests.

Alternatively, you may also view faculty grouped by discipline by visiting individual departmental/program websites, by clicking on the appropriate link(s) below:

Faculty sorted by last name:

A B C D E F G H J K L M N O P R S T U V W X Y Z


Ahern, Gerard P., Ph.D.
Ion channels in pain transmission and immunity

Aisen, Paul S., M.D.
Development of effective therapies for Alzheimer's disease

Albanese, Christopher, Ph.D.
Role of oncogenic signaling and the cyclin D1 gene in the induction and maintenance of breast, prostate, and colon cancer

Amri, Hakima, Ph.D.
Modulation of the peripheral-type benzodiazepine receptor using Ginkgo biloba extract

Andrews, Peter, Ph.D.
Correlation of structure with function in both the normal and pathological kidney; ways to improve the ability of NSAIDs to induce apoptosis of cancer cells

Avantaggiati, Maria Laura, M.D.
Molecular targets for the therapeutic attack of tumor cells; design of small molecules able to interfere with these targets

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Banerjee, Partha, Ph.D.
Prostate cancer prevention, transcriptional regulation of telomerase and telomerase regulated genes

Bayer, Barbara M., Ph.D.
CNS control of immune cell function; opiate-sensitive circuits in midbrain and brainstem

Bellanti, Joseph A., M.D.
Developmental immunology and antimicrobial immunity

Bregman, Barbara S., Ph.D.
Developmental plasticity, neural transplantation, neurotrophic factors, and recovery of function after spinal cord injury; brainstem control of spinal cord function

Burbelo, Peter D., Ph.D.
Serum cancer diagnostics, biomarkers for infection-associated cancers

Byers, Stephen, Ph.D.
Cadherin/catenin adhesion and signaling system in breast and colon cancer and its interaction with nuclear receptors and tumor suppressor genes

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Calderone, Richard A., Ph.D.
Recognition of mammalian cells and signaling events by the human pathogen, Candida albicans

Casey, Elena, Ph.D.
Transcriptional regulation of a class of genes involved in the formation of the early vertebrate body plan

Casey, John L., Ph.D.
Molecular biology of viral hepatitis; RNA structure and function; RNA editing

Chan, Wai-Yee Y., Ph.D.
Molecular genetics of endocrine disorders; developmental genetics and genomics

Chang, Esther H., Ph.D.
Tumor suppressor gene therapy for cancer; tumor-targeted liposome-based systemic gene delivery modulation of oncogene expression by sequence-specific antisense oligonucleotides; molecular bas

Chirikjian, Jack G., Ph.D.
Biotechnology, restriction enzymes, methylases

Cihlar, Ronald L., Ph.D.
Pathogenesis and basic biology of the fungus, Candida albicans

Clarke, Robert, Ph.D., D.Sc.
Breast cancer; malignant progression; gene regulation; steroid hormones and antihormones; drug and endocrine resistance

Cleemann, Lars, Ph.D.
Electrical activity and contraction of myocytes

Cole, Michael F., Ph.D.
Regulation of commensal and exogenous pathogenic bacteria at the mucosal surface by the secretory immune response and the ontogeny of the secretory immune system

Corbin, Joshua, Ph.D.
Genetic and cellular basis of mammalian forebrain development

Cote, Paul J., Ph.D.
Immunobiology and pathogenesis of chronic WHV infection and cisease; virologic, serologic, hepatic, and cellular and molecular immunologic responses in neonatal WHV infection; antiviral and immunotherapy of chronic WHV infection

Crooke, Elliott, Ph.D.
Control of the initiation of chromosomal replication; role of cellular polyphosphates in DNA damage repair

Culty, Martine, Ph.D.
Regulation of male germ cell development and impact of endocrine disrupters on this process

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Danielsen, Mark, Ph.D. 
Steroid receptors in development and disease; biological threat agents

Davidson, Eugene A., Ph.D.
Malaria, biological threat agents, carbohydrates

Djakiew, Daniel, Ph.D.
Role of NGF receptors as oncogenes and tumor suppressors in prostate cancer

Dretchen, Kenneth L., Ph.D.
Neuromuscular and cholinergic pharmacology; central control of respiration and blood pressure; rapid detection of chemical and biological threat agents

Dym, Martin, Ph.D.
Regulation of the renewal and differentiation of spermatogonial stem cells

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Eden, Guinevere F., Ph.D. 
Developmental dyslexia; functional neuroimaging

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Faden, Alan I., M.D.
Chemical pathobiology of CNS injury

Feng, Lixin, Ph.D.
Signaling pathways in regulating male germ-line stem cell differentiation

Finn, Thomas, Ph.D.
Spinal cord injury and the identification of components of the immune system that are both beneficial and detrimental to recovery

Fiszman, Monica L., M.D., Ph.D.
The role of neuronal activity on neural development

Fonzi, William A., Ph.D.
Identification and characterization of the genes and gene products that contribute to the virulence of Candida albicans using molecular genetic techniques

Fricke, Stanely T., Ph.D.
Small animal magnetic resonance imaging and in vivo spectroscopy 

Friedman, Rhonda B., Ph.D.
Aphasia and alexia, neuropsychology of language; functional imaging of language processes

Furth, Priscilla A., Ph.D.
Transgenic mouse models for carcinogenesis, apoptosis, and regulation of cell survival in breast cancer

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Gale, Karen N., Ph.D.
Focally evoked seizures; limbic system and basal ganglia circuits involved in epilepsy, learning and memory

Gallicano, G. Ian, Ph.D.
Cellular adhesion during early mammalian development

Gelmann, Edward P., M.D.
Molecular genetics of prostate cancer, homeodomain proteins and androgen receptor

Gerin, John L., Ph.D.
Molecular and cellular biology of the Hepatitis B and Delta viruses

Gillis, Richard A., Ph.D.|
CNS control of respiration and cardiovascular systems

Glazer, Robert I., Ph.D.
Protein kinase and nuclear receptor regulation of tumorigenesis and stem cell self-renewal

Goldman, Radoslav, Ph.D.
Biomarkers of cancer susceptibility; translational studies of head & neck and prostate cancer

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Haramati, Aviad, Ph.D.
Regulation of renal and, electrolyte physiology during growth; the cardiovascular-renal-endocrine regulation of volume homeostasis in heart failure

Hernandez, Yvonne, Ph.D.
Director of Medical Pharmacology

Herscowitz, Herbert, Ph.D.
Utilization of the immune system to augment novel therapeutic approaches against various forms of cancer

Hilakivi-Clarke, Leena, Ph.D.
Diet, environmental estrogens, and breast cancer prevention; timing of exposure to estrogenic factors

Hoffman, Elizabeth, Ph.D.
Characterization of the neural substrates involved in visual perception and social communication in typically developing individuals and in individuals with autism or dyslexia

Howard, Darlene, Ph.D.
Cognitive neuroscience of aging with emphasis on implicit forms of learning

Huang, Hongzhan, Ph.D.
Bioinformatics and statistical genetics

Huntsman, Molly M., Ph.D.
Functional properties of inhibitory connections in the cerebral cortex

Hurley, Carolyn, Ph.D.
Selection of optimal unrelated donor in hematopoietic stem cell transplantation

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Jessup, John Milburn, M.D.  
Role of scientific research in space, colorectal and pancreatic cancer, and the process of metastasis

Ji, Hong, M.D.

Johnson, Michael D., Ph.D.
Protein c kinase in cancer; transgenic methodology

Jones, Jessica M., Ph.D.
Recombination and ubiquitin conjugation

Jorgensen, Timothy J., Ph.D.
Human repair of radiation-induced DNA damage, and cellular radioresistance

Jung, Mitchel, Ph.D.

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Kanwal, Jagmeet, Ph.D.
Cellular mechanisms and neurodynamics for auditory communication behavior, cortical plasticity and organization, speech recognition and music perception

Kasid, Usha N., Ph.D.
Raf-Erk Signaling; new molecular targets; tumor growth, metastasis and cell survival; breast, prostate and pancreatic cancer

Katchman, Alexander, Ph.D.
Molecular events in cardiac development

Kellar, Kenneth J., Ph.D.
Regulation of neurotransmitter receptors in the central nervous system

Kelley, Matthew, Ph.D.
Identification of the cellular and molecular factors that influence the development of specialized cell types and patterns within the mammalian inner ear

Kitlinska, Joanna B., Ph.D.

Kleinman, Hynda, Ph.D.
Role of the extracellular matrix in cell differentiation and in disease

Kondratyev, Alexei, Ph.D.
Neurotrophic factors; excitatory amino acids

Korba, Brent E., Ph.D.
Therapy and drug discovery for Hepatitis B virus and Hepatitis C virus infection

Kromer, Lawrence, Ph.D.
Neural transplantation and neurotrophic factors and their receptors

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Lechleider, Robert J., M.D.   
TGF beta in vasculogenesis and angiogenesis

Ledley, Robert S., D.D.S.
Computational sciences; development of medical instrumentation, imaging, sterio 3-D analysis; protein sequence database (Protein Information Resource)

Li, LiJun, M.D.

Lumpkin, Michael, Ph.D.
Neuroendocrinology; neuroimmunology and stress; cytokine regulation of neuroendocrine immune systems

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MacArthur, Linda, Ph.D.
Molecular mechanisms by which periods of neuronal activity lead to phenotypic changes in primary sensory neurons

Martin, Mary Beth, Ph.D.
Androgen and estrogen receptors in cancer; endocrine distrupters

Malkova, Ludise, Ph.D.
Neurobiological substrates of learning and memory studied by pharmacological manipulations in nonhuman primates

Maric, Maja, Ph.D.
Antigen processing and presentation of antigens in the context of MHC class II and its effects on autoimmune diseases, tumors and infection; the role of Gamma interferon Inducible Lysosomal Thiol reductase (GILT) in antigen processing

Matsuoka, Yasuji, Ph.D.
Development and mechanism of Alzheimer's disease therapeutic approaches

Medvedev, Andrei, Ph.D.
Electrophysiology, signal analysis and neural network modeling

Mocchetti, Italo, Ph.D.
Regulation of neurotrophic factor expression in the CNS

Morad, Martin, Ph.D.
Ion channels in cardiac tissue

Mueller, Susette C., Ph.D.
Invasion and metastasis, Syk and Src tyrosine kinases, breast cancer, live imaging of tumor cells expressing fluorescent chimeras of invasion-related proteins

Mulroney, Susan E., Ph.D.
Regulation of Ang II AT1 receptors by sex hormones, and the link to development of renal and cardiovascular disease in diabetes; brain to regulation of systemic phosphate homeostasis; renal and cardiovascular effects of herbs

Myers, Adam K., Ph.D.
Cellular mechanisms of platelet and vascular function; mechanisms and mediators of shock, ischemia and thrombosis; alcohol and platelet function

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Nakai, Hiroshi, Ph.D.    
Coordination and regulation of DNA replication, recombination, and repair

Neale, Joseph, Ph.D.
N-acetyl-aspartyl-glutamate (NAAG)/mGluR3 in pain perception, stroke, neurodegenerative disorders and schizophrenia

Nevalainen, Marja T., M.D., Ph.D.
Identification of protein kinase signaling pathways that mediate metastatic spread of prostate cancer cells and progression of prostate cancer to androgen-independence; indentification of mechanisms underlying regulation of growth-promoting kinase signaling pathways in prostate cancer cells by different types of lipids

N'Gouemo, Prosper, Ph.D.
Ion channels, epileptogenesis and epilepsy; neurobiology of alcohol withdrawal seizures and alcohol fetal syndrome

Notario, Vicente, Ph.D.
Oncogenes and molecular biology of growth

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Ojeifo, John O., M.D., Ph.D.    
Angiogenesis, hematopoietic stem cell transplantation, tumor immunology and immunotherapy, genetics, and gene therapy of metastatic breast and prostate cancers

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Padmanabhan, R. Pad, Ph.D.
Molecular mechanisms of RNA replication and polyprotein processing in the Dengue and West Nile viral life cycles

Pak, Daniel, Ph.D.
Molecular mechanisms of synaptic plasticity

Papadopoulos, Vassilios, Ph.D.
Steroid biosynthesis: mechanisms and regulation in health and disease

Pattabiraman, Nagarajan, Ph.D.
Structural analysis and modeling

Peshkin, Beth N., M.S.
Cancer genetic counseling and testing; behavioral outcomes and medical decision-making; ethical issues in genetic counseling and testing

Posch, Phillip, Ph.D.
Impact of cytokine gene polymorphisms on cytokine expression levels, hematopoetic stem cell transplantation and cancer

Preuss, Harry G., M.D.
Minimum inhibitory concentrations of herbal essential oils and monolaurin for gram-positive and gram-negative bacteria

Pscenichkin, Sergei, Ph.D.
Signal transduction via metabotropic glutamate receptors

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Rauschecker, Josef, Ph.D., D.Sc.
Cortical plasticity and reorganization after injury or deprivation; neuronal networks in auditory, somatosensory,and visual cortex

Rebeck, G. William, Ph.D.
Molecular mechanisms of Alzheimer disease using a variety of approaches, including genetics, immunohistochemistry and cell biology

Riegel, Anna T., Ph.D.
Transcriptional control mechanisms involved in hormone and growth factor signaling

Riesenhuber, Maximilian, Ph.D.
Computational modeling, psychophysics and fMRI of object recognition in man, monkey, and machine

Roepe, Paul, Ph.D.
"Multidrug resistant" tumor cells and malarial parasites/Malaria-host interactions

Roman, Beth, Ph.D.
Signals involved in directing developmental vasculogenesis and angiogenesis using the zebrafish as a vertebrate model system

Rosen, Eliot M., M.D., Ph.D.
Function of the breast cancer susceptibility gene-1 BRCA1 in breast and prostate cancer

Rosenthal, Dean S., Ph.D.
Epithelial differentiation; apoptosis; carcinogenesis

Rosenthal, Leonard, Ph.D.
Transforming and anti-transforming activities of human herpesviruses HCMV, HHV-6, and HHV-8 and their association with AIDS/KS

Rui, Hallgeir, M.D., Ph.D.
Translational targeting of Jak-Stat signal transduction for cancer diagnosis, detection and treatment

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Sahibzada, Niaz, Ph.D. 
Central nervous system control of gastrointestinal function

Sandberg, Kathryn, Ph.D.
Sex/gender factors influencing hypertension and renal and vascular disease in terms of disease susceptibility, severity and rate or progression; regulation of the renin angiotensin system, especially, translational control and alternative splicing of angiotensin receptors

Saunders, Pamela, Ph.D.
Communicative coping behaviors in Alzheimer's Disease

Schiffer, Stephen, D.V.M.
Animal models of human genetic disease

Schlegel, C. Richard, M.D., Ph.D.
Biology of cervical cancer, papillomavirus, viral oncology, telomerase, and molecular vaccinology

Schwartz, Barbara, Ph.D.
Cognitive neuropsychiatry and psychopharmacology in patients with Schizophrenia and patients with Alzheimer's Disease

Sherif, Zaki A., Ph.D.
p53 control of gene expression

Sherman, Thomas G., Ph.D.
Neuroendocrine regulation of hypothalamic vasopressin and oxytocin gene expression. Molecular mechanisms of steroid hormone receptor expression and of steroid hormone feedback on neuropeptide genes

Shields, Peter G., M.D.
Carcinogenesis on a genetic and environmental basis in diverse human populations

Sidhu-Hough, Anita, Ph.D.
Neuroscience; dopamine receptors and second messengers

Simbulan-Rosenthal, Cynthia M., Ph.D.
Molecular and biochemical mechanisms in DNA replication, apoptosis and differentiation

Smulson, Mark E., Ph.D.
Molecular biology of poly-ADP-ribosylation; PARP; DNA replication; DNA repair; DNA replication complex; nuclear protein modification; carcinogen interaction

Stoica, Bogdan, M.D.
In vivo protein transduction to the CNS

Suarez-Quian, Carlos, Ph.D.
Molecular fingerprinting analysis of reproductive tissues obtained by laser capture microdissection 

Suzuki, Yuichiro Justin, Ph.D.
Signal transduction and transcriptional regulatory mechanisms for apoptosis and survival or cardiac and smooth muscle cells

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Tang, Careen, Ph.D. 
The EGF family of receptors and its role in breast cancer

Taylor, Christopher, Ph.D.
Signaling in early ovarian follicular development, signaling in ovarian cancer, and follicular steroidogenesis

Tcherkasskaya, Olga V., Ph.D.
Conformational and dynamic properties of biological macromolecules and multi-component biological systems

Teofilovski-Parapid, Gordana, M.D.
Anatomical evaluation of human and monkey coronary circulation

Toretsky, Jeffrey A., M.D.
Understanding the pathogenesis and developing novel therapeutics for pediatric sarcomas, particularly Ewing's Sarcoma

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Ullman, Michael, Ph.D.
Biological and computational bases of normal and disordered language

Underhill, Charles, Ph.D.
Role of the extracellular matrix (ECM) in regulating cell behavior

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Vaidya, Chandan, Ph.D.
Functional neuroimaging of the development of executive control and memory

Verbalis, Joseph G., M.D.
Brainstem and hypothalamic circuitry in neuroendocrine regulation

Vicini, Stefano, Ph.D.
Long-term potentiation and synaptic plasticity; hippocampal circuits and cellular mechanisms of learning

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Waldman, Todd, M.D., Ph.D.
Analysis of tumor suppressor gene function

Wellstein, Anton, M.D., Ph.D.
Angiogenesis factors released from tumor cells as molecularly defined targets for tumor therapy

Wolfe, Barry B., Ph.D.
Subunit regulation of ionotropic receptors for acetylcholine and glutamate

Wrathall, Jean R., Ph.D.
Cellular and chemical factors influencing spinal cord injury and recovery of function

Wroblewski, Jarda T., Ph.D.
Signal transduction via metabotropic glutamate receptors

Wu, Cathy H., Ph.D.
Bioinformatics; proteomics

Wu, Jiang-Young, Ph.D.
Optical imaging of dynamic activity of local neural assemblies; oscillatory patterns and seizuregeneration in cortical circuits

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Xiao, Yingxian, Ph.D.
Molecular studies of nicotinic acetylcholine receptors

Xu, Baoji, Ph.D.
Molecular and neural basis of neurodegenerative diseases and obesity

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Yakovlev, Alexander G., Ph.D.
Molecular basis of phenotypical and physiological heterogeneity of kappa opioid receptors (KOR); mechanisms of secondary tissue damage following traumatic CNS injury

Yao, Zhixing, Ph.D.
Molecular basis of Alzheimer¡¦s disease

Yasuda, Robert P., Ph.D.
Understanding the effects of chronic and prenatal ethanol exposure on the glutamate NMDA receptor subunit complex and metabotropic receptors in the CNS

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Zeffiro, Thomas, M.D., Ph.D.
Neural basis of sensorimotor integration and cognition

Zukowska, Zofia, M.D., Ph.D.
Neuropeptide Y receptor expression; regulation by catecholamines and sex hormones; neuropeptides and monoamines in the peripheral control of cardiovascuar function

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